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America’s Seed Fund October Update – Fall News, Deadlines & Resources for Startups


SBA and America’s Seed Fund Celebrate Manufacturing Month
SBIR/STTR powered by SBA

Don’t Miss…

Discover Federal Resources to Grow Your Export Sales During Manufacturing Month Webinars, October 21 and 28

October is Manufacturing Month and SBA is celebrating by highlighting the resources available to support small manufacturers as they grow their business both domestically and globally. SBA has two remaining webinars featuring exporting and manufacturing experts. On October 21, the Manufacturing Extension Partnership (MEP) will facilitate a discussion on supply chain solutions for small and medium-sized manufacturers. Learn how your company can improve operations, reduce costs, and mitigate risk through effective supply chain management! And October 28 is a Spanish-language webinar that will feature Hispanic-owned manufacturers sharing their export success stories and an overview of federal export promotion resources. Each webinar takes place at 2 p.m. EDT and the registration is live.

Save the Date for NASA SBIR/STTR One-on-Ones November 10 and 17

Those planning to submit a proposal to the NASA SBIR/STTR program’s next Phase I Solicitation (scheduled to come out in January 2022) can prepare by meeting with program representatives. NASA is hosting one-on-one meetings on Wednesday, November 10th, and Wednesday, November 17th, from 12:00 – 4:00 pm ET to give applicants an opportunity to get questions answered ahead of the solicitation release. The meetings will be on a first-come, first-serve basis. Note: One-on-ones are only open to U.S. small businesses, research institutions, and students. Contact the NASA SBIR/STTR Helpdesk at sbir@reisystems.com for additional information or with any questions.

USPTO is Hosting an Event on Intellectual Property Basics for SBIR/STTR Applicants  

On October 28 at 3 pm ET, the U.S. Patent and Trademark Office is hosting a webinar: USPTO Resources for SBIR/STTR Applicants. This webinar is intended for future SBIR/STTR applicants and will provide the basics of patents, trademarks, and copyrights. Many SBIR/STTR applicants are unsure of when to seek intellectual property protections and this webinar will provide initial information and resources for applicants to utilize when preparing their SBIR/STTR proposals. The registration for the event is currently live.  

Last Chance: Connect at the SBIR/STTR Fall Innovation Conference

Registration remains open for the SBIR/STTR Fall Innovation Conference, October 18-20, 2021, in Washington, D.C. The event will convene past, current, and potential SBIR/STTR applicants, as well as researchers, small businesses, and agency officials. There will be opportunities to hear from past SBIR/ STTR awardees and agency SBIR/STTR program managers as they outline funding, strategies, and support for American innovation. The SBIR/ STTR Innovation Conference will run concurrently with the TechConnect World Innovation Conference and Expo.

DoD Seeking Input to Update its Small Business Strategy

The U.S. Department of Defense (DoD) seeks comments and information from the public, particularly small businesses currently in or interested in becoming part of the defense industrial base, to assist in updating its Small Business Strategy. The department is especially interested in information related to the policy objectives on resilience of the U.S. and global supply chains and ensuring equal access to government contracting opportunities. The due date for submitting comments is October 25, 2021, and more information is available in the Federal Register notice.

DOE Requests Information on Commercialization Programming

The U.S. Department of Energy’s (DOE) Office of Technology Transitions (OTT) released a request for information (RFI) on the scope and structure of its commercialization programs. OTT is seeking information related to any experiences or challenges with DOE’s commercialization programs, how they could apply to different technologies, or how to promote diversity, equity, and inclusion. The deadline to respond to the RFI is 3:00 pm ET on January 19, 2022, and instructions on how to submit are available online.


SBIR News & Updates

DOE Phase II Diversity Supplements

DOE SBIR and STTR awardees that receive a Phase II grant are eligible to apply for an administrative diversity supplement to be effective in the summer months of their Phase II during the second year project period. The purpose of the Phase II supplement is to improve the diversity of the research workforce by recruiting and supporting undergraduate and graduate students from groups underrepresented in federal SBIR/STTR research programs. The available template and budget form  should be used to prepare an application for the diversity supplement. All first year Phase II awardees should refer to the Phase II Funding Opportunity Announcement to which they received their Phase II award for full instructions on Phase II awardee eligibility and how and when to submit a diversity supplement.

NIH Support to Diversify Your Workforce

Did you know that the NIH offers funding to diversify the scientific workforce at small businesses participating in the SBIR and STTR programs? If you are a small business with an active SBIR or STTR award, you may be eligible. The diversity supplement for small businesses (PA-21-345) can support students, postdocs, and eligible investigators from diverse backgrounds, including those from groups underrepresented in health-related research or in the SBIR and STTR programs. Find the specific guidelines and a point of contact for your funding institute or center or contact seedinfo@nih.gov with any questions.

STTR-, SBIR-backed Company Goes Public with $2 Billion Valuation

Benson Hill, a unicorn or startup valued at over $1 billion, recently closed its deal to become a public company. Critical to Benson Hill’s initial success were several sources of public capital, including STTR awards from NSF and an SBIR award from USDA. The St. Louis-based agricultural technology company uses machine learning and genome editing to facilitate the production of sustainable and healthy crops.

NOAA awards 35 grants to support Small Business Innovation Research

NOAA’s SBIR Program recently awarded approximately $10.7 million in grants to 35 small businesses to support the development of innovative technologies that support NOAA’s mission and the U.S. economy. Some of the topic areas included in 2021 were uncrewed systems, citizen science and STEM education, fisheries, and weather service improvement. You can visit NOAA’s Technology Partnerships Office website to read more about the recent SBIR awards. The next NOAA SBIR funding opportunity will begin in November. To stay updated on NOAA’s upcoming funding opportunities, follow them on Twitter @NOAAinnovate Twitter @NOAAinnovate and join their mailing list (email NOAA.SBIR@noaa.gov with the subject “subscribe”).

Senate Small Business Committee Hearing Reviews SBIR/STTR Programs

On September 22, the Senate Committee on Small Business and Entrepreneurship held a hearing on “A Review of the SBIR-STTR program.” Jere W. Glover, executive director of the Small Business Technology Council, and Robert Kavetsky, CEO and president of the Energetics Technology Center, provided testimonies on their experiences with the programs. Both witnesses stressed the critical role the programs play for small businesses to compete in areas such as scientific innovation and national security.


Recently Opened SBIR/STTR Funding Opportunities

Dept. of Agriculture (USDA)

 Dept. of Defense (DoD)

Joint DoD SBIR 2021.3/STTR 21.C 

  • Multiple DoD Branches/Components: Closes 10/21/2021.

Army SBIR 21.4 -42, -43, -44

  • Pre-Release: October 12, 2021 (via beta.SAM.gov). Opens: October 26, 2021. Closes: November 30, 2021, at 12:00 pm ET
  • A214-42: Sensor Synthetic Data Generation
  • A214-43: Artificial Intelligence-in Automated Scrap Inspection “MVM”
  • A214-44: Datalink-Enabled AI for Fires Optimization

DARPA SBIR

  • HR001121S0007-27: Next Generation Autonomous and Modular Hardware for Biomanufacturing Platforms in Remote Locations. Opened 9/28/2021. Closes 10/28/2021.
  • HR001121S0007-28: High Throughput Cell Screening Platforms. Opened 9/28/2021. Closes 11/10/2021.
  • HR001121S0007-29: STTR Opportunity: Breakthrough Technologies for Energy Web Dominance. Opened 10/7/2021. Closes 11/30/2021.
  • HR001121S0007-30: SBIR Opportunity: Collaborative APIS Through Incentive Design (CATID). Opened 10/7/2021. Closes 11/30/2021.

Dept. of Health and Human Services (HHS) 

National Science Foundation (NSF)

The last remaining submission window close date is 12/2/2021.


Events & Education

SBIR/STTR Fall Innovation Conference and TechConnect World Innovation Conference and Expo | Oct. 18 – 20, Washington, D.C. | Registration is open.

Two-part NIH SBIR/STTR Proposal Development / Commercialization Strategy / Resources Overview | Session #1 Oct. 19, 1:00 p.m. to 4:30 p.m. ET | and Session #2 Oct. 26, 1:00 p.m. to 4:30 p.m. ET

Spotlight on Manufacturing Webinar Series – Register for Supply Chain Solutions | Oct. 21, 2:00 to 3:00 p.m. ET | or Celebrando el Mes de Fabricantes | Oct. 28, 2:00 to 3:00 p.m. ET

Introduction to the NOAA SBIR Program | Oct. 21, 11 a.m. to 12:30 p.m. ET | Register

Look for upcoming events at sbir.gov/events.


R&D Spotlight

NSTC Seeks Input on Advanced Manufacturing Strategy

On behalf of the National Science and Technology Council (NSTC), the Office of Science and Technology Policy (OSTP) is seeking public input on ways to improve government coordination on advanced manufacturing. The NSTC and OSTP want long-term guidance for federal programs supporting U.S. manufacturing competitiveness and advanced manufacturing R&D that will create jobs, grow the economy across sectors, strengthen national security, enhance sustainability, contribute to climate change challenges, and improve health care. This input will inform OSTP and NSTC as they work with federal agencies and other stakeholders to develop the National Manufacturing Strategic Plan. A series of public events has been organized at various technical conferences (in-person and virtual) from October to December to directly obtain input to the RFI questions. The full text of the RFI with instructions to respond is available in the federal register and responses are due by December 17, 2021.

Useful Stats: Top Industries by State for Net Establishment and Job Creation, 2005-2019

Understanding the industry-level dynamics of business and job creation can help pinpoint which industries in regional economies may be hotspots for innovation activity. This edition of Useful Stats builds on previous SSTI analysis of business and job creation by state and examines data from the Census Bureau’s recently updated Business Dynamics Statistics (BDS) on net establishment and job creation in 2019 at the state and industry levels.

Specifically, this analysis examines net establishment creation and net job creation at the 2-digit NAICS code level. Professional, scientific, and technical services — the industry which contains the most SBIR companies — was the top industry for net establishment creation in 2019 for six states (California, Colorado, Delaware, Nevada, North Dakota, and Wyoming) and the top industry for net job creation in three states (Idaho, Massachusetts, and Virginia). Read the full story here.

Report Outlines Steps for U.S. to Improve Competitiveness in Basic Energy Sciences

The supremacy of the U.S. research enterprise is being challenged by China and other Asian countries, and a new draft report from the Basic Energy Sciences Advisory Committee (BESAC) at the Department of Energy (DOE) concludes that U.S. leadership in basic energy sciences will continue to diminish without intervention. Specifically, the report finds that to stay internationally competitive in basic energy sciences the U.S. must: increase total funding for R&D, spanning from basic and fundamental research to experimental development; focus multi-disciplinary research on several key areas of energy sciences; increase the nation’s ability to attract and retain the world’s top scientists and engineers; and, facilitate interactions among basic, applied, and industrial researchers to accelerate the translation of research into socially beneficial technologies. Read the full story here.


Highlights for Ecosystem Builders

2021 Growth Accelerator and SBIR Catalyst Competitions Award $5.4 Million in Prizes

SBA announced the winners of the 2021 Growth Accelerator and SBIR Catalyst competitions. There are 84 awardees for the Growth Accelerator Fund Competition (GAFC) and eight winners for the SBIR Catalyst competition. This is the first year for the SBIR Catalyst competition and it is aimed at spurring local, regional, and national networks of entrepreneurial support organizations focused on including underrepresented communities within the innovation economy. Together the awardees received $5.4 million in awards to speed the launch, growth, and scale of deep-tech small businesses across the country. The winners come from 48 states, Puerto Rico, the U.S. Virgin Islands, and the District of Columbia, and have been awarded based on their proposals for innovative ideas that inclusively support entrepreneurs researching and developing STEM-related innovations. A full list of the winners is available on SBIR.gov’s accelerator page.


Local Assistance – Meet FAST

The Federal and State Technology (FAST) Partnership Program funded 33 organizations this year, building the SBIR/STTR ecosystem through outreach, technical assistance, and financial support. Meet three of the FAST awardees:

The Center for Innovative Technology (CIT) is the lead organization in Virginia for SBIR/STTR support and features programs that identify and accelerate opportunities for Virginia’s small technology businesses to obtain SBIR, STTR, and other government contracts.

TechConnectWV aims to increase the number of SBIR/STTR proposals and awards to fund innovative technology ideas from West Virginia-based applicants. 

The Wyoming Small Business Development Center Network’s FAST grant will provide specialized training, mentoring, and technical assistance for research and development-focused small businesses.

Find local assistance near you at: sbir.gov/local-assistance.


SBIR Success – re:3D, Inc.’s Onsite Manufacturing Provides Disaster Response via Affordable 3D Printing

In 2017, re:3D’s Houston and Puerto Rico facilities were impacted by hurricanes within a month of each other. From this tragedy, re:3D realized the value onsite manufacturing provides in disaster response/resiliency and the benefits of new job creation, education, and supply chain reduction. SBIR funding from the Air Force provided the necessary resources for the hardware company to complete the significant research required to modify its existing large-scale 3D printers. SBIR funding also enabled re:3D to investigate applications of the hardware to create functional goods from trash which led to the design and printing of functional objects from discarded water bottles. re:3D’s innovation and resilience led to new jobs for those displaced by recent earthquakes and they now have over $8 million in sales and a customer base that includes users from more than 50 countries. re:3D is also a 2020 Tibbetts Award Winner.

Get inspired by more SBIR company stories at sbir.gov/news/success-stories and learn about the 2020 Tibbetts Award winners at https://www.tibbettsawards.com/.


SBIR/STTR Funding Opportunities

Find more funding opportunities and specific topic areas at sbir.gov/funding.

Dept. of Agriculture (USDA)

Dept. of Defense (DoD) All open topics

DARPA SBIR

  • HR001121S007-27 Next Generation Autonomous and Modular Hardware for Biomanufacturing Platforms in Remote Locations. Opened 9/28/2021. Closes 10/28/2021.
  • HR001121S007-28 High Throughput Cell Screening Platforms. Opened 9/28/2021. Closes 10/28/2021.

Joint DoD SBIR 2021.3/STTR 21.C

  • 85 topics opened on 9/21/2021. Closes 10/21/2021.

Dept. of Health and Human Services (HHS)

Targeted funding opportunities from HHS on specific topics with various upcoming due dates can be found here.

National Science Foundation (NSF)


About America’s Seed Fund Update

Our goal is to provide a range of information that will be valuable to the SBIR/STTR programs’ various stakeholders, and future issues will include features on program data, impacts and policies, and more. If you have suggestions, let us know at technology@sba.gov.

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About SBA Office of Innovation and Technology

The U.S. Small Business Administration serves as the coordinating agency for the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs – also known as America’s Seed Fund. SBA also manages the related Federal and State Technology (FAST) Partnership Program and Growth Accelerator Fund Competition. Learn more at sbir.gov.