Treating Hereditary Rare Diseases With In Vivo Precision Genetic Medicines (THRIVE)

The Advanced Research Projects Agency for Health (ARPA-H) Treating Hereditary Rare diseases with In Vivo precision genetic mEdicines (THRIVE) program envisions a future where patients can opt for one-time therapeutic interventions designed to slow, reverse, or cure disease, harnessing revolutionary technologies and a rapidly evolving understanding of the genetic underpinnings of the biological processes that lead to disease.  

Interested parties are invited to review the attached THRIVE Innovative Solutions Opening (ISO) ARPA-H -SOL-25-122.
For detailed information regarding Proposers' Day review Special Notice (SN) ARPA-H-SN-25-131.

Solution summaries are due October 31, 2025, 11:59 PM ET.

For more information about THRIVE, please visit:https://arpa-h.gov/explore-funding/programs/thrive