CRO Services for Single-Cell Multiomics Profiling

NCATS requires a contract research organization (CRO) to perform Human Discovery Panel (HDP) analysis to obtain single-cell multiomic data that shall inform NCATS on transcriptomic and proteomic alterations during inflammatory sensitization in human pluripotent stem cellderived sensory neurons (hPSC-SNs). Capable vendors must prepare and sequence a total of 33 samples (provided by NCATS), and will provide NCATS the data upon completion.
The Contractor shall provide a single-cell multi-nomics platform that allows combined single-cell RNA sequencing with DNA barcoded antibodies that target up to 325 distinct proteins for 33 sample hPSC-SNs under different inflammatory conditions.

Activities shall include the following:
MultiPro Human Discovery Panel; - Quantity 2.
MultiPro Human Enhanced Blocking Reagent; Quantity 8
Genomics Analysis Service; Quantity 1