Assay Service for assessing ADME properties and in vivo PK properties with the selected vendor.

Assay Service for assessing ADME properties and in vivo PK properties with the selected vendor. 

1. The Section on Medicinal Chemistry (SMC) develops new molecular entities with implications in improving health and treatment for various metabolic and alcohol associated diseases. To assess the translational potential of novel molecular entities, which would allow us to make decisions to proceed with the compounds for further development we utilize multiple derisking assays. These assays comprise of both cell-based (in vitro) testing and then eventually in mice to assess pharmacokinetic parameters to see if the drug is orally available.

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